Global Major Depressive Disorder (MDD) Market Size By Product, By Application, By Geographic Scope And Forecast
Report ID: 50843|No. of Pages: 202
Major Depressive Disorder (MDD) Market Size And Forecast
Major Depressive Disorder (MDD) Market size was valued at USD 5.7 Billion in 2024 and is projected to reach USD 10.6 Billion by 2031, growing at a CAGR of 8.4 % during the forecast period 2024-2031.
Global Major Depressive Disorder (MDD) Market Drivers
The market drivers for the Major Depressive Disorder (MDD) Market can be influenced by various factors. These may include:
- MDD’s prevalence and incidence rates are what determine how much demand there is for medical care and prescription drugs. Given that MDD is a prevalent mental health disorder globally, the market size is directly impacted by its prevalence.
- Research and Development: New medicines, therapies, and treatment modalities are developed as a result of research advancements, which propel market expansion. Pharmaceutical firms that fund MDD therapy R&D help to expand the market.
- Regulatory Environment: Modifications to regulations’ rules, clearances, and policies have an impact on the dynamics of the market. The approval of new medications or indications by regulators can have a big impact on market expansion.
- Technological Advancements: By opening up new paths for MDD management, technological innovations in therapeutic modalities like transcranial magnetic stimulation (TMS) and ketamine infusion therapy, as well as diagnostic procedures like brain imaging technologies, have an impact on the market.
- Initiatives for Awareness and Education: Raising public knowledge of mental health issues, such as Major Depressive Disorder (MDD), via advocacy and educational campaigns, can encourage early diagnosis and treatment-seeking behaviour, which in turn can influence the market.
Access to healthcare providers, reimbursement guidelines, and insurance coverage for MDD therapies all have an impact on market expansion. Expanding market potential can be achieved through favourable reimbursement policies and improvements in the healthcare infrastructure. - Demographic Trends: The prevalence of MDD and, consequently, the need for therapies can be influenced by factors such as ageing populations and shifting lifestyles.
Comorbid ailments: Chronic illnesses and anxiety disorders are two examples of medical ailments that frequently coexist with MDD. The treatment landscape and market dynamics are influenced by the prevalence of certain comorbidities. - Economic Factors: A number of economic factors, including insurance coverage, healthcare spending, and income levels, have an impact on the accessibility and affordability of MDD therapies, which in turn has an impact on market growth.
- Patient Preferences and Treatment Outcomes: What drives market trends are patient preferences for particular treatment modalities, such psychotherapy or medication, as well as how well treatments work to achieve desired results.
Global Major Depressive Disorder (MDD) Market Restraints
Several factors can act as restraints or challenges for the Major Depressive Disorder (MDD) Market. These may include:
- Stigma and Awareness: Despite initiatives to increase awareness, there is still stigma associated with mental health conditions like Major Depressive Disorder (MDD). This might prevent people from getting treatment, which in turn restricts the expansion of the market.
- Regulatory Obstacles: Tight guidelines and rigorous approval procedures for novel medications and treatments can hinder the creation and launch of MDD remedies, which will slow the market’s expansion.
- Expensive Medication and Therapy: MDD treatment frequently entails a mix of medication and therapy, which can be costly and may not be accessible to all individuals. This may prevent the market from growing, particularly in areas with poor access to or coverage of healthcare.
- Generic Competition: The introduction of generic copies of antidepressant treatments and the expiration of patents on those products may result in price erosion and lower sales for branded drugs, which may have an effect on the size of the market as a whole.
- Limited Effectiveness of Current Treatments: Although there are a number of MDD treatment choices available, not all individuals will benefit from them, which can cause frustration and necessitate the use of alternative therapies. This restriction may impede market expansion as healthcare practitioners and patients look for more effective therapies.
- Comorbidities and Complexity: Treatment for MDD is frequently complicated by the coexistence of other mental health illnesses or physical ailments. It can be difficult to develop treatments that successfully treat certain comorbidities, which could impede market expansion.
- Risks associated with R&D: Clinical trial failure and the identification of unanticipated adverse effects are two of the inherent risks associated with research and development in the field of mental health. These dangers may discourage funding for novel MDD treatments, which would hinder market expansion.
- Access to Healthcare Services: Inequalities in mental health service accessibility, particularly in underprivileged or rural regions, may restrict the acceptance of MDD therapies and impede their growth.
- Resistance to Treatment: Traditional therapy may not work for certain patients with Major Depressive Disorder (MDD) if they are experiencing treatment-resistant depression. There are obstacles in developing new medicines for this demographic, which could limit market expansion.
Global Major Depressive Disorder (MDD) Market Segmentation Analysis
The Global Major Depressive Disorder (MDD) Market is Segmented on the basis of Product, Application, And Geography.
Major Depressive Disorder (MDD) Market, By Product
- Benzodiazepines
- Antidepressant Drugs
- SSRIs
- SNRIs
- Others
Based on Product, the market is bifurcated into Benzodiazepines, Antidepressant Drugs, SSRIs, SNRIs, and Others. The Antidepressant Drugs segment holds the largest market share during the forecast period. In adults, MDD is common in those who are 25-44 years. Within a complete lifetime, major depression touches 10% – 25% of women and 5% – 12% of men. Thus, increasing population count prone to these diseases is driving the demand for this segment.
Major Depressive Disorder (MDD) Market, By Application
- Clinics
- Hospitals
- Others
Based on Application, the market is bifurcated into Clinics, Hospitals, and Others. The Clinics segment retains the largest market share and is predicted to witness the highest CAGR during the forecast period. People are affected in various ways by major depression. Some people have to feel agitated and irritable, trouble sleeping, and have sudden weight loss. These factors are fueling the demand for this segment during the forecast period.
Major Depressive Disorder (MDD) Market, By Geography
- North America
- Europe
- Asia Pacific
- Rest of the world
Based on Geography, the Global Major Depressive Disorder (MDD) Market is classified into North America, Europe, Asia Pacific, and the Rest of the world. North America holds the largest market share. The expanded awareness about multiple depression conditions in the region. The U.S. represents the biggest market for major depressive disorder (MDD) in North America, accompanied by Canada. In Europe, Germany, France, Italy, and Spain account for a major share of the Major Depressive Disorder (MDD) Market. This market in Asia is anticipated to expand at a notable rate over the forecast years.
Key Players
The major players in the Major Depressive Disorder (MDD) Market are:
- Bristol-Myers Squibb
- Pfizer
- H. Lundbeck
- GlaxoSmithKline
- Sanofi-Aventis
- Merck
- Forest Laboratories
- AstraZeneca
- Johnson & Johnson
- Eli Lily.IBM Corporation
- Cleo Communications, Inc.
- Signiant, Inc.
- Broadcom, Inc.
- Wipro Limited
Report Scope
REPORT ATTRIBUTES | DETAILS |
---|---|
STUDY PERIOD | 2021-2031 |
BASE YEAR | 2024 |
FORECAST PERIOD | 2024-2031 |
HISTORICAL PERIOD | 2021-2023 |
UNIT | Value (USD Billion) |
KEY COMPANIES PROFILED | Bristol-Myers Squibb, Pfizer, H. Lundbeck, GlaxoSmithKline, Sanofi-Aventis, Merck, Forest Laboratories. |
SEGMENTS COVERED |
|
CUSTOMIZATION SCOPE | Free report customization (equivalent to up to 4 analyst’s working days) with purchase. Addition or alteration to country, regional & segment scope. |
Research Methodology of Verified Market Research:
To know more about the Research Methodology and other aspects of the research study, kindly get in touch with our Sales Team at Verified Market Research.
Reasons to Purchase this Report
• Qualitative and quantitative analysis of the market based on segmentation involving both economic as well as non-economic factors
• Provision of market value (USD Billion) data for each segment and sub-segment
• Indicates the region and segment that is expected to witness the fastest growth as well as to dominate the market
• Analysis by geography highlighting the consumption of the product/service in the region as well as indicating the factors that are affecting the market within each region
• Competitive landscape which incorporates the market ranking of the major players, along with new service/product launches, partnerships, business expansions, and acquisitions in the past five years of companies profiled
• Extensive company profiles comprising of company overview, company insights, product benchmarking, and SWOT analysis for the major market players
• The current as well as the future market outlook of the industry with respect to recent developments which involve growth opportunities and drivers as well as challenges and restraints of both emerging as well as developed regions
• Includes in-depth analysis of the market of various perspectives through Porter’s five forces analysis
• Provides insight into the market through Value Chain
• Market dynamics scenario, along with growth opportunities of the market in the years to come
• 6-month post-sales analyst support
Customization of the Report
• In case of any Queries or Customization Requirements please connect with our sales team, who will ensure that your requirements are met.
Frequently Asked Questions
1 INTRODUCTION OF GLOBAL MAJOR DEPRESSIVE DISORDER (MDD) MARKET
1.1 Overview of the Market
1.2 Scope of Report
1.3 Assumptions
2 EXECUTIVE SUMMARY
3 RESEARCH METHODOLOGY OF VERIFIED MARKET RESEARCH
3.1 Data Mining
3.2 Validation
3.3 Primary Interviews
3.4 List of Data Sources
4 GLOBAL MAJOR DEPRESSIVE DISORDER (MDD) MARKET OUTLOOK
4.1 Overview
4.2 Market Dynamics
4.2.1 Drivers
4.2.2 Restraints
4.2.3 Opportunities
4.3 Porters Five Force Model
4.4 Value Chain Analysis
5 GLOBAL MAJOR DEPRESSIVE DISORDER (MDD) MARKET, BY PRODUCT
5.1 Overview
5.2 Benzodiazepines
5.3 Antidepressant Drugs
5.4 SSRIs
5.5 SNRIs
5.6 Others
6 GLOBAL MAJOR DEPRESSIVE DISORDER (MDD) MARKET, BY APPLICATION
6.1 Overview
6.2 Clinics
6.3 Hospitals
6.4 Others
7 GLOBAL MAJOR DEPRESSIVE DISORDER (MDD) MARKET, BY GEOGRAPHY
7.1 Overview
7.2 North America
7.2.1 U.S.
7.2.2 Canada
7.2.3 Mexico
7.3 Europe
7.3.1 Germany
7.3.2 U.K.
7.3.3 France
7.3.4 Rest of Europe
7.4 Asia Pacific
7.4.1 China
7.4.2 Japan
7.4.3 India
7.4.4 Rest of Asia Pacific
7.5 Rest of the World
7.5.1 Latin America
7.5.2 Middle East & Africa
8 GLOBAL MAJOR DEPRESSIVE DISORDER (MDD) MARKET COMPETITIVE LANDSCAPE
8.1 Overview
8.2 Company Market Ranking
8.3 Key Development Strategies
9 COMPANY PROFILES
9.1 Bristol-Myers Squibb
9.1.1 Overview
9.1.2 Financial Performance
9.1.3 Product Outlook
9.1.4 Key Developments
9.2 Pfizer
9.2.1 Overview
9.2.2 Financial Performance
9.2.3 Product Outlook
9.2.4 Key Developments
9.3 H. Lundbeck
9.3.1 Overview
9.3.2 Financial Performance
9.3.3 Product Outlook
9.3.4 Key Developments
9.4 GlaxoSmithKline
9.4.1 Overview
9.4.2 Financial Performance
9.4.3 Product Outlook
9.4.4 Key Developments
9.5 Sanofi-Aventis
9.5.1 Overview
9.5.2 Financial Performance
9.5.3 Product Outlook
9.5.4 Key Developments
9.6 Merck
9.6.1 Overview
9.6.2 Financial Performance
9.6.3 Product Outlook
9.6.4 Key Developments
9.7 Forest Laboratories
9.7.1 Overview
9.7.2 Financial Performance
9.7.3 Product Outlook
9.7.4 Key Developments
9.8 AstraZeneca
9.8.1 Overview
9.8.2 Financial Performance
9.8.3 Product Outlook
9.8.4 Key Developments
9.9 Johnson & Johnson
9.9.1 Overview
9.9.2 Financial Performance
9.9.3 Product Outlook
9.9.4 Key Developments
9.10 Eli Lily
9.10.1 Overview
9.10.2 Financial Performance
9.10.3 Product Outlook
9.10.4 Key Developments
10 Appendix
10.1 Related Research
Report Research Methodology

Verified Market Research uses the latest researching tools to offer accurate data insights. Our experts deliver the best research reports that have revenue generating recommendations. Analysts carry out extensive research using both top-down and bottom up methods. This helps in exploring the market from different dimensions.
This additionally supports the market researchers in segmenting different segments of the market for analysing them individually.
We appoint data triangulation strategies to explore different areas of the market. This way, we ensure that all our clients get reliable insights associated with the market. Different elements of research methodology appointed by our experts include:
Exploratory data mining
Market is filled with data. All the data is collected in raw format that undergoes a strict filtering system to ensure that only the required data is left behind. The leftover data is properly validated and its authenticity (of source) is checked before using it further. We also collect and mix the data from our previous market research reports.
All the previous reports are stored in our large in-house data repository. Also, the experts gather reliable information from the paid databases.

For understanding the entire market landscape, we need to get details about the past and ongoing trends also. To achieve this, we collect data from different members of the market (distributors and suppliers) along with government websites.
Last piece of the ‘market research’ puzzle is done by going through the data collected from questionnaires, journals and surveys. VMR analysts also give emphasis to different industry dynamics such as market drivers, restraints and monetary trends. As a result, the final set of collected data is a combination of different forms of raw statistics. All of this data is carved into usable information by putting it through authentication procedures and by using best in-class cross-validation techniques.
Data Collection Matrix
Perspective | Primary Research | Secondary Research |
---|---|---|
Supplier side |
|
|
Demand side |
|
|
Econometrics and data visualization model

Our analysts offer market evaluations and forecasts using the industry-first simulation models. They utilize the BI-enabled dashboard to deliver real-time market statistics. With the help of embedded analytics, the clients can get details associated with brand analysis. They can also use the online reporting software to understand the different key performance indicators.
All the research models are customized to the prerequisites shared by the global clients.
The collected data includes market dynamics, technology landscape, application development and pricing trends. All of this is fed to the research model which then churns out the relevant data for market study.
Our market research experts offer both short-term (econometric models) and long-term analysis (technology market model) of the market in the same report. This way, the clients can achieve all their goals along with jumping on the emerging opportunities. Technological advancements, new product launches and money flow of the market is compared in different cases to showcase their impacts over the forecasted period.
Analysts use correlation, regression and time series analysis to deliver reliable business insights. Our experienced team of professionals diffuse the technology landscape, regulatory frameworks, economic outlook and business principles to share the details of external factors on the market under investigation.
Different demographics are analyzed individually to give appropriate details about the market. After this, all the region-wise data is joined together to serve the clients with glo-cal perspective. We ensure that all the data is accurate and all the actionable recommendations can be achieved in record time. We work with our clients in every step of the work, from exploring the market to implementing business plans. We largely focus on the following parameters for forecasting about the market under lens:
- Market drivers and restraints, along with their current and expected impact
- Raw material scenario and supply v/s price trends
- Regulatory scenario and expected developments
- Current capacity and expected capacity additions up to 2027
We assign different weights to the above parameters. This way, we are empowered to quantify their impact on the market’s momentum. Further, it helps us in delivering the evidence related to market growth rates.
Primary validation
The last step of the report making revolves around forecasting of the market. Exhaustive interviews of the industry experts and decision makers of the esteemed organizations are taken to validate the findings of our experts.
The assumptions that are made to obtain the statistics and data elements are cross-checked by interviewing managers over F2F discussions as well as over phone calls.

Different members of the market’s value chain such as suppliers, distributors, vendors and end consumers are also approached to deliver an unbiased market picture. All the interviews are conducted across the globe. There is no language barrier due to our experienced and multi-lingual team of professionals. Interviews have the capability to offer critical insights about the market. Current business scenarios and future market expectations escalate the quality of our five-star rated market research reports. Our highly trained team use the primary research with Key Industry Participants (KIPs) for validating the market forecasts:
- Established market players
- Raw data suppliers
- Network participants such as distributors
- End consumers
The aims of doing primary research are:
- Verifying the collected data in terms of accuracy and reliability.
- To understand the ongoing market trends and to foresee the future market growth patterns.
Industry Analysis Matrix
Qualitative analysis | Quantitative analysis |
---|---|
|
|