Global Total Knee Replacement Market Size By Type (Primary, Partial, Revision), By Procedure (Traditional, Minimally Invasive, Computer-assisted), By Material (Metal Alloy, Ceramic, Polymer), By End-user (Hospitals, Ambulatory Surgical Centers, Orthopedic Clinics), By Geographic Scope And Forecast

Report ID: 141776|No. of Pages: 202

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Global Total Knee Replacement Market Size By Type (Primary, Partial, Revision), By Procedure (Traditional, Minimally Invasive, Computer-assisted), By Material (Metal Alloy, Ceramic, Polymer), By End-user (Hospitals, Ambulatory Surgical Centers, Orthopedic Clinics), By Geographic Scope And Forecast

Report ID: 141776|Published Date: Nov 2024|No. of Pages: 202|Base Year for Estimate: 2024|Format:   Report available in PDF formatReport available in Excel Format

Total Knee Replacement Market Size and Forecast

Total Knee Replacement Market size was valued at USD 9.92 Billion in 2024 and is projected to reach USD 15.37 Billion by 2031, growing at a CAGR of 6.2% from 2024 to 2031.

  • Total knee replacement (TKR), also known as total knee arthroplasty, is a surgical technique that replaces damaged or diseased knee joint components with artificial ones to relieve pain and restore function. This operation is recommended for individuals with severe osteoarthritis, rheumatoid arthritis, or knee injuries who have not responded to conservative treatments such as drugs or physical therapy.
  • TKR is intended to treat chronic pain, increase mobility, and improve the overall quality of life for those who have substantial limits in their everyday activities owing to knee dysfunction.

Total Knee Replacement Market is estimated to grow at a CAGR of 6.2% & reach US$ 15.37 Bn by the end of 2031

Global Total Knee Replacement Market Dynamics

The key market dynamics that are shaping the total knee replacement market include:

Key Drivers

  • Aging Population and Increased Prevalence of Osteoarthritis: The global aging population is a primary driver of the total knee replacement market, as older persons are more likely to have osteoarthritis and other knee-related problems. According to the United Nations, the number of people aged 65 and older is expected to reach 1.5 billion by 2050, more than double the 2019 total of 703 million. According to the Centers for Disease Control and Prevention (CDC), more than 32.5 million persons in the United States suffer from osteoarthritis, with knee osteoarthritis being one of the most frequent. According to the Arthritis Foundation, one in every two persons may develop symptoms of knee osteoarthritis during their lifetime, underlining the growing demand for knee replacement surgeries.
  • Rising Obesity Rates and Associated Knee Problems: Obesity rates are rising all over the world, increasing the frequency of knee-related disorders and driving demand for knee replacement surgeries. The World Health Organization (WHO) says that global obesity has nearly tripled since 1975, with more than 1.9 billion persons classed as overweight in 2016. According to a study published in the Journal of Bone and Joint Surgery, individuals with a BMI above 30 kg/m² are 20 times more likely to require a total knee replacement than those with a normal BMI. The link between obesity and knee replacements is an important element in market growth.
  • Technological Advancements in Knee Implants and Surgical Techniques: Implant design and surgical processes are improving, making total knee replacements more effective and appealing to patients. According to the American Academy of Orthopaedic Surgeons (AAOS), more than 90% of modern total knee replacements continue to operate well 15 years after surgery. This trend is exemplified by the increasing acceptance of robotics-assisted knee replacement surgeries, which are expected to grow at a CAGR of more than 20% between 2024 and 2031, according to Verified Market Research.

Key Challenges:

  • High Cost of Surgery: Knee replacement surgeries cost between $30,000 and $50,000 in the United States, making them too expensive for many patients, particularly those who do not have enough insurance coverage. This financial barrier stops people from getting critical operations, resulting in prolonged discomfort and worsened ailments. As a result, many patients postpone surgery until their diseases require more complex and expensive treatments.
  • Shortage of Skilled Healthcare Professionals: The total knee replacement market faces difficulty because of a shortage of skilled medical professionals. As demand for these treatments grows, particularly among the younger and more active populations, the scarcity of experienced orthopedic surgeons impedes timely access to care. This shortage causes longer surgical wait times and has a negative influence on patient outcomes, as immediate intervention is critical for optimal recovery and rehabilitation.

Key Trends:

  • Adoption of Robotic-assisted Surgery: The use of robotic-assisted surgery is a major trend in the total knee replacement market. This technology improves precision and accuracy during surgeries, allowing surgeons to personalize operations to each patient’s anatomy. Robotic technologies, such as the VELYS™ and ROSA® platforms, offer real-time data and 3D modeling, reducing human error and improving surgical outcomes. As these technologies advance, they are projected to become standard practice, significantly enhancing patient recovery times and satisfaction.
  • Development of Smart Knee Implants: The development of smart knee implants, such as Persona IQ®, is another significant trend. These modern implants integrate sensors that monitor a patient’s activity and recovery measures, allowing healthcare personnel to track them remotely. This data-driven method allows for tailored treatment plans and prompt responses if difficulties occur. As the desire for more connected healthcare solutions rises, smart implants are anticipated to gain popularity among both patients and surgeons.

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Global Total Knee Replacement Market Regional Analysis

Here is a more detailed regional analysis of the total knee replacement market:

North America:

  • According to Verified Market Research, North America is estimated to dominate in total knee replacement market over the forecast period. North America, particularly the United States, has a large population suffering from osteoarthritis and obesity, both of which are important risk factors for knee replacement surgery. According to the Centers for Disease Control and Prevention (CDC), around 32.5 million persons in the United States have osteoarthritis, with knee osteoarthritis being the most frequent type. According to the CDC, 42.4% of American adults were obese between 2017 and 2018. A study published in the Journal of Bone and Joint Surgery indicated that persons with a BMI over 30 kg/m² are 20 times more likely to need a total knee replacement. The high prevalence of risk factors fuels the region’s demand for total knee replacements.
  • Furthermore, North America has a sophisticated healthcare system with large healthcare expenditures, allowing for wider access to knee replacement treatments. The Centers for Medicare and Medicaid Services estimate that healthcare spending in the United States exceeded $4.1 trillion in 2020, or $12,530 per person. This accounts for 19.7% of the country’s gross domestic product. The American Academy of Orthopaedic Surgeons (AAOS) reports that over 600,000 knee replacements are performed in the United States each year. This large volume of procedures is enabled given the region’s superior healthcare infrastructure and spending.

Asia Pacific:

  • The Asia Pacific region is estimated to exhibit the highest growth within the market during the forecast period. Obesity, a major risk factor for knee osteoarthritis, is quickly increasing in the Asia-Pacific region. The World Obesity Federation predicts that by 2025, obesity prevalence will be 14.8% in China, 24.9% in Australia, and 10.8% in Japan. According to a study published in the Asia Pacific Journal of Clinical Nutrition, the prevalence of overweight and obesity in Asia-Pacific grew from 25.0% to 35.7% between 2000 and 2016. This trend is likely to increase the incidence of knee-related disorders, hence boosting the growth of the total knee replacement market.
  • Furthermore, the Asia Pacific region is undergoing a large demographic transition toward an older population, which is a primary driver of knee replacement surgeries. According to the United Nations Economic and Social Commission for Asia and the Pacific (UNESCAP), the region’s elder population (aged 60 and more) is predicted to more than quadruple, from 630 million in 2020 to around 1.3 billion by 2050. According to the World Health Organization (WHO), osteoarthritis affects around 10.3% of men and 19.4% of women over the age of 60 in China. This rising older population, which has a high prevalence of osteoarthritis, is pushing up demand for total knee replacements in the region.

Global Total Knee Replacement Market: Segmentation Analysis

The Total Knee Replacement Market is segmented based on Type, Procedure, Material, End-User, and Geography.

Total Knee Replacement Market Segmentation Analysis

Total Knee Replacement Market, By Type

  • Primary
  • Partial
  • Revision

Based on Type, the market is segmented into Primary, Partial, and Revision. The primary segment is estimated to dominate the total knee replacement market. This dominance is fueled by the rising prevalence of severe osteoarthritis and other degenerative knee disorders in elderly populations, necessitating efficient surgical procedures. Primary knee replacements are a long-term option for people with chronic knee discomfort, considerably increasing mobility and quality of life. As healthcare knowledge increases and more people seek treatment, this segment is projected to maintain its market leadership.

Total Knee Replacement Market, By Procedure

  • Traditional
  • Minimally Invasive
  • Computer-assisted

Based on Procedure, the market is segmented into Traditional, Minimally Invasive, and Computer-assisted. The traditional segment is estimated to dominate the total knee replacement market owing to the extensive use of total knee arthroplasty, a well-known surgical option for patients with severe knee problems, especially osteoarthritis. Furthermore, the aging population and rising prevalence of knee problems contribute to ongoing demand for this surgery, supporting its market dominance.

Total Knee Replacement Market, By Material

  • Metal Alloys
  • Ceramics
  • Polymers

Based on Material, the market is divided into Metal Alloys, Ceramics, and Polymers. The metal alloys segment is estimated to dominate the market over the forecast period due to their known reliability and longevity, with surgeons placing a high faith in materials such as cobalt-chromium and titanium. Metal alloys provide superior mechanical qualities, biocompatibility, and long-term performance, making them the chosen material for knee replacements. Their solid track record inspires trust in both healthcare professionals and patients, resulting in continuing demand in this segment.

Total Knee Replacement Market, By End-User

  • Hospitals
  • Ambulatory Surgical Centers
  • Orthopedic Clinics

Based on End-User, the Total Knee Replacement Market is divided into Hospitals, Ambulatory Surgical Centers, and Orthopedic Clinics. The hospital segment is estimated to dominate the market over the forecast period due to hospitals’ extensive infrastructure, which includes cutting-edge surgical equipment and a diverse spectrum of specialist medical personnel. Hospitals are better able to perform complex procedures and provide extended postoperative care, thus they are the preferred option for patients undergoing knee replacement surgery. As the demand for these operations grows, hospitals are well-positioned to serve the expanding patient population.

Total Knee Replacement Market, By Geography

  • North America
  • Europe
  • Asia Pacific
  • Rest of the World

Based on Geography, the total knee replacement market is classified into North America, Europe, Asia Pacific, and the Rest of the World. North America is estimated to dominate the market during the forecast period owing to an aging population and a high frequency of knee-related illnesses such as osteoarthritis and rheumatoid arthritis. The region benefits from modern healthcare infrastructure, access to cutting-edge surgical procedures, and a large number of prominent orthopedic equipment manufacturers. As a result, North America is likely to maintain its market dominance due to strong demand for knee replacement surgery and novel treatment options.

Key Players

The “Total Knee Replacement Market” study report will provide valuable insight with an emphasis on the global market. The major players in the market are Zimmer, Inc., DePuy Synthes, Stryker, Smith & Nephew, Exactech, Inc., Corin Group, Aesculap Implants Systems LLC, Medacta International, Allegra Orthopaedics Limited, and Kinamed, Inc.

Our market analysis also entails a section solely dedicated to such major players wherein our analysts provide an insight into the financial statements of all the major players, along with product benchmarking and SWOT analysis. The competitive landscape section also includes key development strategies, market share, and market ranking analysis of the above-mentioned players globally.

Total Knee Replacement Market Recent Developments

Total Knee Replacement Market Key Developments

  • In August 2021, a U.S. Food and Drug Administration (FDA) De Novo classification grant and authorization were announced by Zimmer Biomet Holdings, Inc. and Canary Medical for the marketing of the tibial extension for Persona IQ, the world’s first and only smart knee cleared by the FDA for total knee replacement surgery.
  • In June 2021, FDA clearance of Ortho Development’s Balanced Knee System and TriMax implants with Think Surgical’s TSolution One Total Knee Application was announced by Think Surgical Inc. and Ortho Development Corporation.

Report Scope

REPORT ATTRIBUTESDETAILS
Study Period

2021-2031

Base Year

2024

Forecast Period

2024-2031

Historical Period

2021-2023

Unit

Value in USD Billion

Key Companies Profiled

Zimmer, Inc., DePuy Synthes, Stryker, Smith & Nephew, Exactech, Inc., Corin Group, Aesculap Implants Systems LLC, Medacta International, Allegra Orthopaedics Limited, and Kinamed, Inc.

Segments Covered

By Type, By Procedure, By Material, By End-User, and By Geography.

Customization scope

Free report customization (equivalent to up to 4 analyst’s working days) with purchase. Addition or alteration to country, regional & segment scope.

Research Methodology of Verified Market Research:

Research Methodology of VMR

To know more about the Research Methodology and other aspects of the research study, kindly get in touch with our Sales Team at Verified Market Research.

Reasons to Purchase this Report

• Qualitative and quantitative analysis of the market based on segmentation involving both economic as well as non-economic factors
• Provision of market value (USD Billion) data for each segment and sub-segment
• Indicates the region and segment that is expected to witness the fastest growth as well as to dominate the market
• Analysis by geography highlighting the consumption of the product/service in the region as well as indicating the factors that are affecting the market within each region
• Competitive landscape which incorporates the market ranking of the major players, along with new service/product launches, partnerships, business expansions, and acquisitions in the past five years of companies profiled
• Extensive company profiles comprising of company overview, company insights, product benchmarking, and SWOT analysis for the major market players
• The current as well as the future market outlook of the industry with respect to recent developments which involve growth opportunities and drivers as well as challenges and restraints of both emerging as well as developed regions
• Includes in-depth analysis of the market of various perspectives through Porter’s five forces analysis
• Provides insight into the market through Value Chain
• Market dynamics scenario, along with growth opportunities of the market in the years to come
• 6-month post-sales analyst support

Customization of the Report

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Frequently Asked Questions

Total Knee Replacement Market size was valued at USD 9.92 Billion in 2024 and is projected to reach USD 15.37 Billion by 2031, growing at a CAGR of 6.2% from 2024 to 2031.

The growth of the total knee replacement market is driven by factors such as the increasing prevalence of knee-related disorders and advancements in surgical techniques and implant materials.

The major players are Zimmer, Inc., DePuy Synthes, Stryker, Smith & Nephew, Exactech, Inc., Corin Group, Aesculap Implants Systems LLC, Medacta International, Allegra Orthopaedics Limited, and Kinamed, Inc.

The Total Knee Replacement Market is segmented based on Type, Procedure, Material, End-User, and Geography.

The sample report for the Total Knee Replacement Market can be obtained on demand from the website. Also, the 24*7 chat support & direct call services are provided to procure the sample report.

1 INTRODUCTION OF GLOBAL TOTAL KNEE REPLACEMENT MARKET
1.1 Overview of the Market
1.2 Scope of Report
1.3 Assumptions

2 EXECUTIVE SUMMARY

3 RESEARCH METHODOLOGY OF VERIFIED MARKET RESEARCH
3.1 Data Mining
3.2 Validation
3.3 Primary Interviews
3.4 List of Data Sources

4 GLOBAL TOTAL KNEE REPLACEMENT MARKET OUTLOOK
4.1 Overview
4.2 Market Dynamics
4.2.1 Drivers
4.2.2 Restraints
4.2.3 Opportunities
4.3 Porters Five Force Model
4.4 Value Chain Analysis

5 GLOBAL TOTAL KNEE REPLACEMENT MARKET, BY PRODUCT TYPE
5.1 Overview
5.2 Primary Knee Replacement Systems
5.3 Revision Knee Replacement Systems
5.4 Partial Knee Replacement Systems

6 GLOBAL TOTAL KNEE REPLACEMENT MARKET, BY IMPLANT TYPE
6.1 Overview
6.2 Fixed–bearing Implants
6.3 Mobile–bearing Implants
6.4 Medial Pivot Implants
6.5 Others

7 GLOBAL TOTAL KNEE REPLACEMENT MARKET, BY PROCEDURE
7.1 Overview
7.2 Total Knee Arthroplasty
7.3 Partial Knee Arthroplasty
7.4 Revision Knee Arthroplasty

8 GLOBAL TOTAL KNEE REPLACEMENT MARKET, BY END-USE
8.1 Overview
8.2 Hospitals
8.3 Orthopedic Clinics
8.4 Ambulatory Surgical Centers
8.5 Others

9 GLOBAL TOTAL KNEE REPLACEMENT MARKET, BY GEOGRAPHY
9.1 Overview
9.2 North America
9.2.1 U.S.
9.2.2 Canada
9.2.3 Mexico
9.3 Europe
9.3.1 Germany
9.3.2 U.K.
9.3.3 France
9.3.4 Rest of Europe
9.4 Asia Pacific
9.4.1 China
9.4.2 Japan
9.4.3 India
9.4.4 Rest of Asia Pacific
9.5 Rest of the World
9.5.1 Latin America
9.5.2 Middle East and Africa

10 GLOBAL TOTAL KNEE REPLACEMENT MARKET COMPETITIVE LANDSCAPE
10.1 Overview
10.2 Company Market Ranking
10.3 Key Development Strategies

11 COMPANY PROFILES

11.1 Zimmer Inc.
11.1.1 Overview
11.1.2 Financial Performance
11.1.3 Product Outlook
11.1.4 Key Developments

11.2 DePuy Synthes
11.2.1 Overview
11.2.2 Financial Performance
11.2.3 Product Outlook
11.2.4 Key Developments

11.3 Stryker
11.3.1 Overview
11.3.2 Financial Performance
11.3.3 Product Outlook
11.3.4 Key Developments

11.4 Smith and Nephew
11.4.1 Overview
11.4.2 Financial Performance
11.4.3 Product Outlook
11.4.4 Key Developments

11.5 Exactech Inc.
11.5.1 Overview
11.5.2 Financial Performance
11.5.3 Product Outlook
11.5.4 Key Developments

11.6 Corin Group
11.6.1 Overview
11.6.2 Financial Performance
11.6.3 Product Outlook
11.6.4 Key Developments

11.7 Aesculap Implants Systems LLC
11.7.1 Overview
11.7.2 Financial Performance
11.7.3 Product Outlook
11.7.4 Key Developments

11.8 Medacta International
11.8.1 Overview
11.8.2 Financial Performance
11.8.3 Product Outlook
11.8.4 Key Developments

11.9 Allegra Orthopaedics Limited
11.9.1 Overview
11.9.2 Financial Performance
11.9.3 Product Outlook
11.9.4 Key Developments

11.10 Kinamed Inc.
11.10.1 Overview
11.10.2 Financial Performance
11.10.3 Product Outlook
11.10.4 Key Developments

12 KEY DEVELOPMENTS
12.1 Product Launches/Developments
12.2 Mergers and Acquisitions
12.3 Business Expansions
12.4 Partnerships and Collaborations

13 Appendix
13.1 Related Research

Report Research Methodology

Research methodology

Verified Market Research uses the latest researching tools to offer accurate data insights. Our experts deliver the best research reports that have revenue generating recommendations. Analysts carry out extensive research using both top-down and bottom up methods. This helps in exploring the market from different dimensions.

This additionally supports the market researchers in segmenting different segments of the market for analysing them individually.

We appoint data triangulation strategies to explore different areas of the market. This way, we ensure that all our clients get reliable insights associated with the market. Different elements of research methodology appointed by our experts include:

Exploratory data mining

Market is filled with data. All the data is collected in raw format that undergoes a strict filtering system to ensure that only the required data is left behind. The leftover data is properly validated and its authenticity (of source) is checked before using it further. We also collect and mix the data from our previous market research reports.

All the previous reports are stored in our large in-house data repository. Also, the experts gather reliable information from the paid databases.

expert data mining

For understanding the entire market landscape, we need to get details about the past and ongoing trends also. To achieve this, we collect data from different members of the market (distributors and suppliers) along with government websites.

Last piece of the ‘market research’ puzzle is done by going through the data collected from questionnaires, journals and surveys. VMR analysts also give emphasis to different industry dynamics such as market drivers, restraints and monetary trends. As a result, the final set of collected data is a combination of different forms of raw statistics. All of this data is carved into usable information by putting it through authentication procedures and by using best in-class cross-validation techniques.

Data Collection Matrix

PerspectivePrimary ResearchSecondary Research
Supplier side
  • Fabricators
  • Technology purveyors and wholesalers
  • Competitor company’s business reports and newsletters
  • Government publications and websites
  • Independent investigations
  • Economic and demographic specifics
Demand side
  • End-user surveys
  • Consumer surveys
  • Mystery shopping
  • Case studies
  • Reference customer

Econometrics and data visualization model

data visualiztion model

Our analysts offer market evaluations and forecasts using the industry-first simulation models. They utilize the BI-enabled dashboard to deliver real-time market statistics. With the help of embedded analytics, the clients can get details associated with brand analysis. They can also use the online reporting software to understand the different key performance indicators.

All the research models are customized to the prerequisites shared by the global clients.

The collected data includes market dynamics, technology landscape, application development and pricing trends. All of this is fed to the research model which then churns out the relevant data for market study.

Our market research experts offer both short-term (econometric models) and long-term analysis (technology market model) of the market in the same report. This way, the clients can achieve all their goals along with jumping on the emerging opportunities. Technological advancements, new product launches and money flow of the market is compared in different cases to showcase their impacts over the forecasted period.

Analysts use correlation, regression and time series analysis to deliver reliable business insights. Our experienced team of professionals diffuse the technology landscape, regulatory frameworks, economic outlook and business principles to share the details of external factors on the market under investigation.

Different demographics are analyzed individually to give appropriate details about the market. After this, all the region-wise data is joined together to serve the clients with glo-cal perspective. We ensure that all the data is accurate and all the actionable recommendations can be achieved in record time. We work with our clients in every step of the work, from exploring the market to implementing business plans. We largely focus on the following parameters for forecasting about the market under lens:

  • Market drivers and restraints, along with their current and expected impact
  • Raw material scenario and supply v/s price trends
  • Regulatory scenario and expected developments
  • Current capacity and expected capacity additions up to 2027

We assign different weights to the above parameters. This way, we are empowered to quantify their impact on the market’s momentum. Further, it helps us in delivering the evidence related to market growth rates.

Primary validation

The last step of the report making revolves around forecasting of the market. Exhaustive interviews of the industry experts and decision makers of the esteemed organizations are taken to validate the findings of our experts.

The assumptions that are made to obtain the statistics and data elements are cross-checked by interviewing managers over F2F discussions as well as over phone calls.

primary validation

Different members of the market’s value chain such as suppliers, distributors, vendors and end consumers are also approached to deliver an unbiased market picture. All the interviews are conducted across the globe. There is no language barrier due to our experienced and multi-lingual team of professionals. Interviews have the capability to offer critical insights about the market. Current business scenarios and future market expectations escalate the quality of our five-star rated market research reports. Our highly trained team use the primary research with Key Industry Participants (KIPs) for validating the market forecasts:

  • Established market players
  • Raw data suppliers
  • Network participants such as distributors
  • End consumers

The aims of doing primary research are:

  • Verifying the collected data in terms of accuracy and reliability.
  • To understand the ongoing market trends and to foresee the future market growth patterns.

Industry Analysis Matrix

Qualitative analysisQuantitative analysis
  • Global industry landscape and trends
  • Market momentum and key issues
  • Technology landscape
  • Market’s emerging opportunities
  • Porter’s analysis and PESTEL analysis
  • Competitive landscape and component benchmarking
  • Policy and regulatory scenario
  • Market revenue estimates and forecast up to 2027
  • Market revenue estimates and forecasts up to 2027, by technology
  • Market revenue estimates and forecasts up to 2027, by application
  • Market revenue estimates and forecasts up to 2027, by type
  • Market revenue estimates and forecasts up to 2027, by component
  • Regional market revenue forecasts, by technology
  • Regional market revenue forecasts, by application
  • Regional market revenue forecasts, by type
  • Regional market revenue forecasts, by component

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